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Surgical complications due to postnatal cytomegalovirus infection in a preterm infant with malrotation
Anaïs Torregrossa1, Olivier Reinberg2, Leonor Alamo3
1Clinics of Neonatology, University Hospital and University of Lausanne, Switzerland.
Insights
Extremely preterm infants with intestinal malrotation may develop systemic cytomegalovirus (CMV) infection, requiring surgery and antiviral therapy. Suspect CMV in preterm infants with prolonged GI issues, especially when fed non-pasteurized breast milk.
Area of Science:
- Neonatology
- Pediatric Infectious Diseases
- Gastroenterology
Background:
- Extremely preterm infants are vulnerable to infections.
- Intestinal malrotation can complicate infant feeding and health.
- Postnatal cytomegalovirus (CMV) infection is a concern in preterm neonates.
Abstract:
We report a case of an extremely preterm infant with intestinal malrotation who contracted postnatal systemic cytomegalovirus (CMV) infection with a complicated intestinal evolution requiring repeated surgical interventions and antiviral treatment. This report is to emphasize that prolonged gastrointestinal symptoms in extremely preterm infants fed with non-pasteurized breast milk should lead to suspicion of CMV infection. The importance of preventive measures when feeding very preterm infants with breast milk needs to be considered. Furthermore, the indications for antiviral treatment, in particular in preterm infants, need to be clarified.
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