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Prolidase Enzyme Activity in Conjunctiva and Pterygium Tissues
Yıldıray Yıldırım1, Abdullah Kaya1, Taner Kar1
1Department of Ophthalmology, GATA Haydarpasa Training Hospital, Istanbul, Turkey.
Background:
The aim of this study was to determine prolidase activity in conjunctival tissue and its relationship with pterygium.
Material And Methods:
Prolidase activity was measured in 23 pterygium and 25 healthy conjunctival tissues and the 2 groups were compared.
Results:
Prolidase enzyme activity could not be measured in either the healthy conjunctival or in pterygium tissues. The mean serum prolidase levels of the control and pterygium groups were 967.46±353.64 and 858.29±301.83, respectively. Statistically, there was no significant difference between the groups with regard to serum prolidase levels (p>0.05).
Conclusions:
In conclusion, absence of prolidase activity in pterygium tissue indicates that there is no collagen turnover in this tissue. We may explain this finding with the elastin-rich structure of the conjunctiva.
