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HCV Council--critical appraisal of data: recommendations for clinical practice in a rapidly evolving therapeutic

Nancy Reau1, Michael W Fried2, David R Nelson3

  • 1Rush University Medical Center, Chicago, IL, USA.

Liver International : Official Journal of the International Association for the Study of the Liver
|October 29, 2015
PubMed

Insights

This review summarizes expert opinions on managing chronic hepatitis C virus (HCV) infection, offering guidance for clinicians. It highlights areas needing further research for optimal patient care strategies.

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Clinical Practice Guidelines

Background:

  • The Hepatitis C Virus (HCV) Council convenes experts to assess current data on chronic HCV management.
  • This 2014 meeting built upon the findings of the 2011 HCV Council.

Purpose of the Study:

  • To critically evaluate existing data on best practices for managing chronic hepatitis C virus (HCV) infection.
  • To develop clinical practice statements addressing areas of controversy with significant clinical impact.

Main Methods:

  • Literature review by faculty to support or refute proposed statements.
  • Expert faculty voted on the evidence and support level for each statement after comprehensive discussion.

Main Results:

  • The article summarizes the detailed analysis and expert opinions presented at the HCV Council 2014.
  • Key findings and consensus statements regarding chronic HCV management are outlined.

Conclusions:

  • Optimal management strategies for specific patient populations and clinical situations in chronic HCV infection require further investigation.
  • The article provides evidence-based expert opinion to guide clinicians while new data emerges.
Abstract

Keywords:
direct-acting antiviralgenotype 1a and 1bgenotype 2genotype 3hepatitis C virus

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