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Ocriplasmin use in a selected case with preserved visual acuity
Settimio Rossi1, Ada Orrico2, Paolo Melillo3
1Multidisciplinary Department of Medical, Surgical and Dental Sciences, Eye Clinic, Second University of Naples, Via Sergio Pansini, 5, 80131, Naples, Italy. settimio.rossi@unina2.it.
BMC Ophthalmology
|October 30, 2015
Summary
Intravitreal Ocriplasmin safely treated vitreo-macular traction in a patient with 20/20 vision, improving macular function. This case highlights Ocriplasmin
Area of Science:
- Ophthalmology
- Pharmacological treatment
- Retinal imaging and electrophysiology
Background:
- Vitreo-macular traction (VMT) is a condition affecting central vision.
- Previous Ocriplasmin studies focused on patients with reduced visual acuity.
- This study presents the first case of Ocriplasmin treatment for VMT in a patient with 20/20 visual acuity.
Observation:
- A 67-year-old female with VMT and 20/20 visual acuity received Ocriplasmin injection.
- Pre-treatment symptoms included metamorphopsia.
- Post-treatment, optical coherence tomography confirmed VMT release and multifocal electroretinogram showed improved retinal density responses.
Findings:
- Ocriplasmin injection led to anatomical recovery and symptom resolution.
- Functional macular recovery was evidenced by a significant increase in multifocal electroretinogram responses.
- Visual acuity remained stable at 20/20 post-treatment.
Implications:
- Intravitreal Ocriplasmin is a safe and effective treatment for VMT, even in patients with excellent visual acuity.
- Anatomical VMT release correlates with functional macular recovery.
- Further research with broader inclusion criteria and larger sample sizes is warranted.
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