Related Experiment Video
Updated: Mar 31, 2026
Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
Published on: October 31, 2025
Gastric remnant cancer: A distinct entity or simply another proximal gastric cancer?
Thuy B Tran1, Ioannis Hatzaras2, David J Worhunsky1
1Department of Surgery, Stanford University, Stanford Cancer Institute, Stanford, California.
Background:
The purpose of this study was to compare outcomes following resection of gastric remnant (GRC) and conventional gastric cancer.
Methods:
Patients who underwent resection for gastric cancer in 8 academic institutions from 2000-2012 were evaluated to compare morbidity, mortality, and survival based on history of prior gastrectomy.
Results:
Of the 979 patients who underwent gastrectomy with curative-intent during the 12-year study period, 55 patients (5.8%) presented with GRC and 924 patients (94.4%) presented with conventional gastric cancer. Patients with GRC were slightly older (median 69 vs. 66 years). GRC was associated with higher rates of complication (56% vs. 41%, P = 0.028), longer operative times (301 vs. 237 min, P < 0.001), higher intraoperative blood loss (300 vs. 200 ml, P = 0.012), and greater need for blood transfusion (43% vs. 23%, P = 0.001). There were no significant differences in 30-day (3.6% vs. 4%) or 90-day mortality (9% vs. 8%) between the two groups. Overall survival rates were similar between GRC and conventional gastric cancer (5-year 20.3% vs. 38.6%, P = 0.446). Multivariate analysis revealed that history of gastrectomy was not predictive of survival while established predictors (older age, advanced T-stage, nodal involvement, blood transfusion, multivisceral resection, and any complication) were associated with poor survival.
Conclusions:
Despite higher morbidity, prognosis after resection of gastric remnant cancer is similar to conventional gastric cancer.
