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A randomized, double-blind study to compare tenoxicam with sustained release indomethacin in osteoarthritic patients
P A Hooper1, K O'Brien, S Spence
1Medical Department, Roche Products Ltd, Welwyn Garden City, UK.
The Journal of International Medical Research
|January 1, 1989
Abstract:
A total of 144 patients were recruited for this randomized, double-blind study to compare the efficacy and tolerance of tenoxicam and sustained release indomethacin in patients with osteoarthritis. The results show that 20 mg/day tenoxicam is equal in efficacy to, and significantly better tolerated than, 75 mg/day sustained release indomethacin. Patients receiving tenoxicam recorded significantly better global tolerance ratings (P = 0.042) and fewer adverse events than those receiving indomethacin.