Related Experiment Video
Updated: Mar 31, 2026

Using Flexible Gold-Titanium Reaction Cells to Simulate Pressure-Dependent Microbial Activity in the Context of Subsurface Biomining
Published on: October 5, 2019
Metal release from stainless steel in biological environments: A review
Yolanda S Hedberg1, Inger Odnevall Wallinder2
1KTH Royal Institute of Technology, School of Chemical Science and Engineering, Department of Chemistry, Division of Surface and Corrosion Science, Drottning Kristinas väg 51, Stockholm SE-100 44, Sweden and Unit of Occupational and Environmental Dermatology, Institute of Environmental Medicine, Karolinska Institutet, Box 210, Stockholm SE-171 77, Sweden.
Abstract:
Due to its beneficial corrosion resistance, stainless steel is widely used in, e.g., biomedical applications, as surfaces in food contact, and for products intended to come into skin contact. Low levels of metals can be released from the stainless steel surface into solution, even for these highly corrosion resistant alloys. This needs to be considered in risk assessment and management. This review aims to compile the different metal release mechanisms that are relevant for stainless steel when used in different biological settings. These mechanisms include corrosion-induced metal release, dissolution of the surface oxide, friction-induced metal release, and their combinations. The influence of important physicochemical surface properties, different organic species and proteins in solution, and of biofilm formation on corrosion-induced metal release is discussed. Chemical and electrochemical dissolution mechanisms of the surface oxides of stainless steel are presented with a focus on protonation, complexation/ligand-induced dissolution, and reductive dissolution by applying a perspective on surface adsorption of complexing or reducing ligands and proteins. The influence of alloy composition, microstructure, route of manufacture, and surface finish on the metal release process is furthermore discussed as well as the chemical speciation of released metals. Typical metal release patterns are summarized.
Related Concept Videos
Microbial Corrosion
Microbial Leaching
Microbes and Other Elemental Cycles
Physical Methods for Controlling Microbial Growth: Radiation and Filtration

