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Tripe palms and malignancy.

P R Cohen1, M E Grossman, L Almeida

  • 1Department of Dermatology, College of Physicians and Surgeons, Columbia University, New York, New York.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
|May 1, 1989
PubMed
Summary
This summary is machine-generated.

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Tripe palms, a skin condition, are strongly linked to cancer, often appearing before diagnosis. Prompt medical evaluation for malignancy is crucial for patients presenting with tripe palms.

Area of Science:

  • Dermatology
  • Oncology
  • Clinical Medicine

Background:

  • Tripe palms are a rare dermatological condition characterized by thickened, velvety palms with prominent dermatoglyphics.
  • This condition can be idiopathic or associated with underlying malignancies.

Observation:

  • A review of 77 cases revealed that 94% of patients with tripe palms had cancer.
  • Tripe palms frequently co-occurred with acanthosis nigricans (77% of cases).

Findings:

  • In cancer patients with isolated tripe palms, pulmonary carcinoma was the most common malignancy (53%).
  • When tripe palms and acanthosis nigricans co-occurred, gastric carcinoma was frequent (35%).
  • Tripe palms presented as the initial sign of malignancy in over 40% of cases.

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Implications:

  • Patients with tripe palms require thorough diagnostic work-up to detect potential underlying cancers.
  • Early detection of malignancy is possible through the recognition of tripe palms as a presenting sign.
  • Pulmonary and gastric carcinomas are particularly associated with tripe palms, necessitating targeted screening.