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Primary cardiac lymphoma: two cases and a review of literature
Karolis Jonavicius1,2,3, Kestutis Salcius4, Raimundas Meskauskas5
1Faculty of Medicine, Vilnius University, Vilnius, Lithuania. karolismd@gmail.com.
Insights
Primary cardiac lymphoma, a rare heart tumor, presents diagnostic and treatment challenges. Chemotherapy is the primary treatment, with surgery sometimes needed for hemodynamic support.
Area of Science:
- Cardiology
- Oncology
- Pathology
Background:
- Primary cardiac lymphoma is an extremely rare extra-nodal non-Hodgkin's lymphoma.
- Diffuse large B-cell lymphoma is the most common subtype, often affecting the right heart chambers.
- Early diagnosis and treatment are crucial for survival.
Observation:
- This report details two cases of primary cardiac lymphoma in female patients.
- One patient achieved remission post-treatment, while the other unfortunately died.
- The cases highlight diagnostic and therapeutic complexities.
Findings:
- Chemotherapy is currently the most effective treatment for primary cardiac lymphoma.
- Surgical intervention may be required for palliative care, particularly to address hemodynamic compromise.
- The role of cardiac surgery in managing this rare malignancy is significant.
Implications:
- Increased awareness of primary cardiac lymphoma is essential for timely diagnosis.
- Multidisciplinary approaches involving oncology, cardiology, and cardiac surgery are vital.
- Further research into optimal treatment strategies for this rare condition is warranted.
Background:
Primary cardiac lymphoma is one of the rarest tumours of the heart. It belongs to the extra-nodal non-Hodgkin's lymphomas. The most common type of this tumour is diffuse large B cell lymphoma. Usually, right atrium and right ventricle are involved. This tumour is fatal unless diagnosed and treated in time. In this article two female patients who were diagnosed with primary cardiac lymphoma and treated at our clinic are described. The first patient went to remission after the treatment, while the second patient died. The goals of this article are to show the difficulties of diagnosing and treating this disease, the role of cardiac surgery in its treatment and to raise awareness of this disease.
Case Reports:
In this article two female patients who were diagnosed with primary cardiac lymphoma and treated at our clinic are described. The first patient went to remission after the treatment, while the second patient died.
Conclusions:
Primary cardiac lymphoma is a very rare disease. At the moment the most effective treatment is chemotherapy. Palliative surgery may be necessary to correct hemodynamics when venous blood flow to the lungs is disturbed.
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