Related Experiment Video
Updated: Mar 31, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
A preliminary investigation into whether early intervention can improve weight loss among those initially
Jessica L Unick1, Leah Dorfman2, Tricia M Leahey3
1Weight Control and Diabetes Research Center, The Miriam Hospital, Brown Medical School, 196 Richmond Street, Providence, RI, 02903, USA. junick@lifespan.org.
Abstract:
This study examined whether providing additional support to individuals with poor initial weight loss improves 12-week outcomes. Participants were randomized to a 12-week internet-delivered behavioral weight loss program (IBWL; n = 50) or the identical internet program plus the possibility of extra support (IBWL + ES; n = 50). IBWL + ES participants losing <2.3% at Week 4 (early non-responders; n = 12) received one individual meeting and two follow-up phone calls with an interventionist, and were compared to IBWL 'early non-responders' who did not receive extra support (n = 21), and to 'early responders' in both treatment arms (i.e., 4-week weight loss ≥2.3%; n = 59). IBWL + ES early non-responders had greater program adherence (p's < 0.055) and lost twice as much weight (p = 0.036) compared to IBWL early non-responders. Program adherence did not differ between early responders and IBWL + ES early non-responders. However, 12-week weight loss was greater in the early responders compared to both early non-responder groups (p's > 0.05). Providing additional intervention to early non-responders in an Internet program improves treatment outcomes.
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