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Updated: Mar 31, 2026

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
Published on: July 14, 2015
Fit3D: a web application for highly accurate screening of spatial residue patterns in protein structure data
Florian Kaiser1, Alexander Eisold1, Sebastian Bittrich1
1Department of Applied Computer and Biosciences, University of Applied Sciences Mittweida, 09648 Mittweida, Germany.
Unlabelled:
The clarification of linkage between protein structure and function is still a demanding process and can be supported by comparison of spatial residue patterns, so-called structural motifs. However, versatile up-to-date resources to search for local structure similarities are rare. We present Fit3D, an easily accessible web application for highly accurate screening of structural motifs in 3D protein data.
Availability And Implementation:
The web application is accessible at https://biosciences.hs-mittweida.de/fit3d and program sources of the command line version were released under the terms of GNU GPLv3. Platform-independent binaries and documentations for offline usage are available at https://bitbucket.org/fkaiser/fit3d
Contact:
florian.kaiser@hs-mittweida.de
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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