Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

X-ray Crystallography02:18

X-ray Crystallography

26.9K
The size of the unit cell and the arrangement of atoms in a crystal may be determined from measurements of the diffraction of X-rays by the crystal, termed X-ray crystallography.
Diffraction
Diffraction is the change in the direction of travel experienced by an electromagnetic wave when it encounters a physical barrier whose dimensions are comparable to those of the wavelength of the light. X-rays are electromagnetic radiation with wavelengths about as long as the distance between neighboring...
26.9K
Determination of Crystal Structures01:29

Determination of Crystal Structures

104
In the late 1800s, the revelation that light extended beyond visible wavelengths led to the discovery of X-rays by Wilhelm Roentgen. Recognized as high-energy electromagnetic radiation with short wavelengths, X-rays prompted exploration into their interaction with crystals. Max von Laue proposed in 1912 that the periodic arrangement of atoms, ions, or molecules in crystals would cause them to diffract X-rays, a hypothesis confirmed through experiments with copper sulfate and zinc sulfide...
104
Total Internal Reflection Fluorescence Microscopy01:05

Total Internal Reflection Fluorescence Microscopy

13.7K
Total internal reflection fluorescence microscopy or TIRF is an advanced microscopic technique used to visualize fluorophores in samples close to a solid surface with a higher refractive index, such as a glass coverslip. TIRF only allows fluorophores in proximity to the solid surface to be excited. When light from a medium with a lower refractive index (such as air) hits the glass coverslip at a critical angle, the light undergoes total internal reflection stead of passing through the glass.
13.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Immunosuppressive therapies adversely affect blood biochemical parameters in patients with inflammatory bowel disease: a meta-analysis.

The Journal of international medical research·2019
Same author

Facile synthesis of Ag-CuO/SBA-15 for aerobic epoxidation of olefins with high activity.

Nanotechnology·2019
Same author

Reinforcement of Polylactic Acid for Fused Deposition Modeling Process with Nano Particles Treated Bamboo Powder.

Polymers·2019
Same author

Comparison of deep learning and human observer performance for detection and characterization of simulated lesions.

Journal of medical imaging (Bellingham, Wash.)·2019
Same author

Bending Flexibility of Moso Bamboo (<i>Phyllostachys Edulis</i>) with Functionally Graded Structure.

Materials (Basel, Switzerland)·2019
Same author

CT Super-Resolution GAN Constrained by the Identical, Residual, and Cycle Learning Ensemble (GAN-CIRCLE).

IEEE transactions on medical imaging·2019
Same journal

Decomposition-based harmonization for quantitative PET imaging across scanners and radiotracers.

Medical physics·2026
Same journal

Development and evaluation of an in vivo dose-based monitoring system for electron FLASH radiation therapy.

Medical physics·2026
Same journal

A novel optical respiratory gating system with a hybrid phase-amplitude algorithm for spot-scanning proton therapy.

Medical physics·2026
Same journal

Gamma Knife treatment planning using knowledge-based reinforcement learning.

Medical physics·2026
Same journal

Development and characterization of a novel, small animal external beam irradiator using a clinical high dose rate brachytherapy source.

Medical physics·2026
Same journal

Deep learning-based dose prediction for MR-guided prostate SIB: Supporting rapid feasibility assessment and adaptive editing margin selection.

Medical physics·2026
See all related articles

Related Experiment Video

Updated: Mar 31, 2026

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating
10:39

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating

Published on: October 11, 2016

10.2K

Spherical grating based x-ray Talbot interferometry.

Wenxiang Cong1, Yan Xi1, Ge Wang1

  • 1Biomedical Imaging Center, Rensselaer Polytechnic Institute, Troy, New York 12180.

Medical Physics
|November 2, 2015
PubMed
Summary
This summary is machine-generated.

Spherical grating interferometry enhances x-ray imaging by improving signal visibility and dose efficiency. This advanced technique offers a larger field of view for preclinical and clinical applications compared to traditional planar gratings.

More Related Videos

A Multimodal Wide-Field Fourier-Transform Raman Microscope
06:48

A Multimodal Wide-Field Fourier-Transform Raman Microscope

Published on: December 30, 2025

750
Synchrotron X-ray Microdiffraction and Fluorescence Imaging of Mineral and Rock Samples
10:12

Synchrotron X-ray Microdiffraction and Fluorescence Imaging of Mineral and Rock Samples

Published on: June 19, 2018

9.7K

Related Experiment Videos

Last Updated: Mar 31, 2026

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating
10:39

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating

Published on: October 11, 2016

10.2K
A Multimodal Wide-Field Fourier-Transform Raman Microscope
06:48

A Multimodal Wide-Field Fourier-Transform Raman Microscope

Published on: December 30, 2025

750
Synchrotron X-ray Microdiffraction and Fluorescence Imaging of Mineral and Rock Samples
10:12

Synchrotron X-ray Microdiffraction and Fluorescence Imaging of Mineral and Rock Samples

Published on: June 19, 2018

9.7K

Area of Science:

  • Medical Imaging
  • Physics
  • Materials Science

Background:

  • Grating interferometry offers advanced x-ray imaging, capturing attenuation, phase shift, and scattering.
  • Phase-contrast and dark-field imaging excel in soft tissue visualization but are limited by point-like x-ray sources and planar gratings.
  • Current methods face limitations in photon flux, signal visibility, and field of view.

Purpose of the Study:

  • To adapt planar x-ray grating imaging principles for a spherical grating configuration.
  • To expand the capabilities of x-ray grating interferometry for broader applications.
  • To overcome the limitations of planar gratings in x-ray imaging.

Main Methods:

  • Theoretical analysis of the Talbot effect for spherical grating interferometry.
  • Development of a spherical grating that aligns with point x-ray source wave fronts.
  • Implementation of an efficient imaging method for extracting attenuation, differential phase, and dark-field data.

Main Results:

  • Theoretical framework for spherical grating Talbot self-imaging derived using the Rayleigh-Sommerfeld diffraction formula.
  • Demonstration of periodic angular distribution in polar coordinates for Talbot patterns.
  • Numerical simulations confirm spherical grating interferometer self-imaging, aligning with theoretical predictions.

Conclusions:

  • Spherical grating x-ray Talbot interferometry shows significant clinical and preclinical promise.
  • Offers a larger field of view compared to planar grating imaging.
  • Enhances signal visibility and dose utilization in x-ray imaging.