Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Balsa Wood-Loaded Polyvinyl Alcohol/Chitosan/Zinc Gluconate Hydrogel Applied as Wound Dressing.

Polymers·2026
Same author

<i>Massilia varians</i> P2-4: a potential biocontrol agent against pathogenic <i>Pseudomonas aeruginosa</i> in <i>Eriocheir sinensis</i>.

Frontiers in microbiology·2026
Same author

Supportive care needs and associated factors in hemodialysis patients: a cross-sectional study.

International urology and nephrology·2026
Same author

The Adherence Paradox in Uncontrolled Moderate-To-Severe Asthma: A Qualitative Study of Patient Experiences and Unmet Needs.

Research in nursing & health·2026
Same author

The Impact of Child Life Intervention on Psychological Status and Quality of Life in Children With Cleft Lip and Palate.

The Journal of craniofacial surgery·2026
Same author

A coumarin-based water-soluble fluorescent probe for tandem detection of Cu<sup>2+</sup> and glutathione with application in bioimaging and real sample analysis.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2026

Related Experiment Video

Updated: Mar 30, 2026

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

21.9K

A novel polydimethylsiloxane microfluidic viscometer fabricated using microwire-molding.

Misha Zou1, Shaoxi Cai1, Zhenli Zhao1

  • 1Bioengineering College, Chongqing University, Chongqing 400044, China.

The Review of Scientific Instruments
|November 2, 2015
PubMed
Summary

This study introduces an affordable microfluidic viscometer for biological fluids, utilizing minimal sample volumes. The device offers accurate viscosity measurements, crucial for lab-on-a-chip applications.

More Related Videos

A Microfluidic Platform to Study Bioclogging in Porous Media
05:10

A Microfluidic Platform to Study Bioclogging in Porous Media

Published on: October 13, 2022

2.7K
Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles
11:54

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Published on: March 13, 2017

9.9K

Related Experiment Videos

Last Updated: Mar 30, 2026

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

21.9K
A Microfluidic Platform to Study Bioclogging in Porous Media
05:10

A Microfluidic Platform to Study Bioclogging in Porous Media

Published on: October 13, 2022

2.7K
Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles
11:54

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Published on: March 13, 2017

9.9K

Area of Science:

  • Biomedical Engineering
  • Fluid Dynamics
  • Microfluidics

Background:

  • Accurate viscosity measurement is vital for biological fluid analysis and lab-on-a-chip (LOC) systems.
  • Existing viscometers can be expensive, require large sample volumes, or lack portability.

Purpose of the Study:

  • To develop and validate an economical microfluidic viscometer for precise viscosity measurements of biological fluids.
  • To enable viscosity analysis with low sample volumes (<200 μl) for improved LOC integration.

Main Methods:

  • Fabrication of a polydimethylsiloxane (PDMS) microchip viscometer using a microwire-molding technique.
  • Monitoring fluid flow velocity via camera and analyzing liquid column movement with MATLAB video processing.
  • Calibration with deionized water and validation against a traditional glass capillary viscometer.

Main Results:

  • The microfluidic viscometer accurately measures viscosity down to 0.69 mPa·s.
  • Measurements showed >98% agreement with NIST data for water across temperatures.
  • Comparison with glass capillary viscometry yielded <1% average relative error for various biological and chemical solutions.

Conclusions:

  • The developed microfluidic viscometer is economical, accurate, and requires minimal sample volumes.
  • It demonstrates high precision for biological fluids, including cell suspensions (RSD <1.5%).
  • This device is suitable for integration into LOC systems, aiding simulation and control.