Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

14.4K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
14.4K
Olfaction01:25

Olfaction

49.8K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
49.8K
Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

14.1K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
14.1K
Anatomy of Respiratory System I: Upper Respiratory Tract01:29

Anatomy of Respiratory System I: Upper Respiratory Tract

6.4K
The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....
6.4K
Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

29
The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more...
29
Respiratory System Abnormal Finding II: Palpation and Auscultation01:31

Respiratory System Abnormal Finding II: Palpation and Auscultation

2.0K
In assessing respiratory abnormalities, palpation and auscultation are critical tools for detecting and interpreting various pathophysiological changes. These techniques provide insight into underlying disorders by evaluating tactile sensations and sounds produced by the respiratory system.
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

REFCOR guidelines on the management of olfactory neuroblastoma: A formalized expert consensus.

European annals of otorhinolaryngology, head and neck diseases·2026
Same author

Sinonasal squamous cell carcinoma: REFCOR guidelines for diagnosis, treatment and follow-up.

European annals of otorhinolaryngology, head and neck diseases·2026
Same author

REFCOR guidelines for sinonasal adenocarcinoma.

European annals of otorhinolaryngology, head and neck diseases·2026
Same author

Sinonasal mucosal melanoma: REFCOR guidelines for diagnosis, treatment and follow-up.

European annals of otorhinolaryngology, head and neck diseases·2026
Same author

REFCOR good practice guidelines for radiotherapy in sinonasal carcinomas and mucosal melanomas.

European annals of otorhinolaryngology, head and neck diseases·2026
Same author

REFCOR guidelines for sinus and nasal cavity cancer.

European annals of otorhinolaryngology, head and neck diseases·2026

Related Experiment Video

Updated: Mar 30, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
07:00

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

Published on: February 28, 2019

6.4K

Respiratory epithelial adenomatoid hamartomas and olfactory function.

C Nagouas, P L Bastier, L De Gabory

    Revue De Laryngologie - Otologie - Rhinologie
    |November 3, 2015
    PubMed
    Summary

    Respiratory epithelial adenomatoid hamartoma (REAH) surgery improved olfaction and decreased corticosteroid use. REAH co-existence with nasal polyposis may be overestimated, as inflammation did not strongly correlate with outcomes.

    More Related Videos

    An Effective Manual Deboning Method To Prepare Intact Mouse Nasal Tissue With Preserved Anatomical Organization
    15:40

    An Effective Manual Deboning Method To Prepare Intact Mouse Nasal Tissue With Preserved Anatomical Organization

    Published on: August 10, 2013

    38.4K
    Isolating Nasal Olfactory Stem Cells from Rodents or Humans
    09:19

    Isolating Nasal Olfactory Stem Cells from Rodents or Humans

    Published on: August 22, 2011

    31.6K

    Related Experiment Videos

    Last Updated: Mar 30, 2026

    Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
    07:00

    Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

    Published on: February 28, 2019

    6.4K
    An Effective Manual Deboning Method To Prepare Intact Mouse Nasal Tissue With Preserved Anatomical Organization
    15:40

    An Effective Manual Deboning Method To Prepare Intact Mouse Nasal Tissue With Preserved Anatomical Organization

    Published on: August 10, 2013

    38.4K
    Isolating Nasal Olfactory Stem Cells from Rodents or Humans
    09:19

    Isolating Nasal Olfactory Stem Cells from Rodents or Humans

    Published on: August 22, 2011

    31.6K

    Area of Science:

    • Otolaryngology
    • Pathology

    Background:

    • Respiratory epithelial adenomatoid hamartoma (REAH) can present independently or alongside various diseases.
    • A hypothesis suggests REAH is a non-specific nasal response to impaired olfaction.

    Purpose of the Study:

    • To investigate the relationship between REAH, nasal polyposis, and olfactory function.
    • To evaluate the impact of REAH surgery on olfaction and corticosteroid consumption.

    Main Methods:

    • Retrospective study of patients with REAH undergoing surgery.
    • Analysis of pre- and post-operative olfaction, corticosteroid use, and polyp histology.
    • Comparison of REAH with and without polyps, and literature data.

    Main Results:

    • 28 patients had REAH, 18 with polyps. Olfactory function improved post-surgery (p < 0.01).
    • Nasal corticosteroid consumption decreased post-surgery (p < 0.02).
    • Polyp recurrence was 11%, REAH recurrence was 0%.

    Conclusions:

    • Olfactory function, cellular infiltration, and polyp recurrence are often not correlated with inflammatory processes in REAH.
    • The association of nasal polyposis with REAH might be overestimated.