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Sellar Masses: An Epidemiological Study.

Khaled Al-Dahmani1, Syed Mohammad2, Fatima Imran2

  • 11Department of Medicine,Tawam Hospital in affiliation with Johns Hopkins,Al Ain,United Arab Emirates.

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
|November 3, 2015
PubMed
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This summary is machine-generated.

Sellar masses (SM) affect 0.1% of the population, with pituitary adenomas being most common. This study provides the first comprehensive North American epidemiology of SM, highlighting the need for further research and resource allocation.

Area of Science:

  • Endocrinology
  • Neuroscience
  • Public Health

Background:

  • Sellar masses (SM) are common pituitary and nonpituitary growths.
  • Epidemiology of SM in North America remains understudied.

Purpose of the Study:

  • To determine the epidemiology of sellar masses in Nova Scotia, Canada.
  • To establish population prevalence and incidence rates for various types of SM.

Main Methods:

  • Prospective data collection of pituitary referrals from November 2005.
  • Retrospective analysis of patients with SM between November 2005 and December 2013.
  • Utilized computerized registries for comprehensive patient identification.

Main Results:

  • Identified 1107 patients with SM, a population prevalence of 0.1%.
Keywords:
pituitary adenomaspituitary tumo

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  • Pituitary adenomas accounted for 83% of SM, with nonfunctioning and prolactinomas being most prevalent.
  • Common presenting features included incidental findings, headaches, and vision loss; hormonal deficiencies were frequent.

    • Conclusions:

    • This study represents the largest North American epidemiological assessment of SM in a stable population.
    • The significant prevalence of SM necessitates further research into their natural history and management.
    • Findings support the need for optimized resource allocation for SM care.