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Neuromyelitis Optica (NMO) with Abdominal Tuberculosis (TB)
Shaheen A Bhatty1, Hari Lal1, Abu Talib1
1Department of Medicine, Dow Medical College, Karachi.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|November 3, 2015
Summary
Neuromyelitis Optica (NMO), a rare autoimmune disorder, can present with acute paraplegia. This case highlights an unusual association between NMO and abdominal tuberculosis, emphasizing the need for broader diagnostic considerations.
Area of Science:
- Neuroimmunology
- Infectious Diseases
Background:
- Neuromyelitis Optica (NMO) is an autoimmune disorder affecting the central nervous system, primarily the optic nerves and spinal cord.
- While NMO's pathogenesis involves humoral immunity, its co-occurrence with infections like tuberculosis (TB) is rarely documented.
Observation:
- A young female presented with acute paraplegia, diagnosed with NMO.
- During hospitalization, she developed ascites, later confirmed to be caused by Mycobacterium tuberculosis.
Findings:
- This case presents a rare association between abdominal tuberculosis and Neuromyelitis Optica.
- The co-occurrence suggests potential shared or interacting pathophysiological mechanisms.
Implications:
- Highlights the importance of considering infectious etiologies, such as abdominal TB, in NMO patients presenting with atypical symptoms.
- Underscores the need for further research into the interplay between autoimmune neurological disorders and infectious agents like Mycobacterium tuberculosis.
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