Amyloidosis with Multiple Myeloma Presenting with Acromegalic Features
Shaheen A Bhatty1, Abdul Samad Siddiqui1, Abu Talib1
1Department of Medicine, Dow Medical College, Civil Hospital, Karachi.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|November 3, 2015
Summary
Amyloidosis and multiple myeloma are part of the same plasma cell disorder spectrum. This case highlights a rare instance where amyloidosis preceded an incidental multiple myeloma diagnosis in an elderly female.
Area of Science:
- Hematology
- Oncology
Background:
- Amyloidosis and multiple myeloma are clonal plasma cell disorders.
- Amyloidosis can be localized or systemic, affecting multiple organs.
Observation:
- A case report of an elderly female with long-standing amyloidosis causing facial disfigurement and neuropathy.
- The patient presented with concomitant multiple myeloma, diagnosed incidentally.
Findings:
- The multiple myeloma was asymptomatic and discovered incidentally.
- This presentation suggests a potential link or progression pathway between amyloidosis and multiple myeloma.
Implications:
- Understanding the spectrum of clonal plasma cell disorders is crucial for early diagnosis.
- This case underscores the importance of considering multiple myeloma even in the absence of typical symptoms when amyloidosis is present.
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