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The Thyroid Gland01:23

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
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Related Experiment Video

Updated: Mar 30, 2026

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
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Long-term outcomes after total thyroidectomy.

Pernille Vita Fooken Jensen1, Søren Mudie Jelstrup, Preben Homøe

  • 1pfooken@hotmail.com.

Danish Medical Journal
|November 3, 2015
PubMed
Summary
This summary is machine-generated.

Total thyroidectomy complications in Denmark show similar recurrent laryngeal nerve palsy rates but higher bleeding. Permanent hypoparathyroidism (low calcium) is a significant concern requiring management guidelines.

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Area of Science:

  • Endocrinology
  • Surgical Outcomes
  • Thyroid Surgery

Background:

  • Assessing complication rates of total thyroidectomy in a Danish regional hospital.
  • Investigating long-term outcomes for managing hypoparathyroidism post-surgery.

Purpose of the Study:

  • Evaluate complication rates: permanent hypoparathyroidism, recurrent laryngeal nerve palsy, and post-operative bleeding.
  • Analyze long-term hypoparathyroidism management outcomes.

Main Methods:

  • Retrospective study of 114 patients undergoing total thyroidectomy for benign thyroid disease.
  • Data collection on nerve palsy, bleeding, and calcium levels.

Main Results:

  • Permanent recurrent laryngeal nerve palsy: 0.9%; temporary: 1.8%.
  • Post-operative bleeding: 5.4%.
  • Temporary hypocalcaemia: 22.8%; permanent: 17.4%. Autotransplantation: 23.7%; unintentional parathyroidectomy: 8.7%.

Conclusions:

  • Recurrent laryngeal nerve palsy rates are comparable to other studies.
  • Post-operative bleeding incidence is higher than reported elsewhere.
  • High permanent hypocalcaemia rates necessitate guideline development for calcium and vitamin D supplementation management.