Related Experiment Video
Updated: Mar 30, 2026

Isolation of Human Primary Valve Cells for In vitro Disease Modeling
Published on: April 16, 2021
An Incidentally Discovered Pedunculated Degenerative Cyst on the Aortic Valve
Ashwin K Thiagarajasubramanian1, Sandip K Zalawadiya2, Luis C Afonso2
1Internal Medicine Department, Wayne State University, Detroit, Michigan.
Abstract:
We report the case of a pedunculated cystic mass on the aortic valve discovered in a patient presenting for a routine echocardiogram. The highly mobile nature of the mass warranted prompt surgical removal to prevent cardioembolic complications. The mass was preoperatively thought to be a papillary fibroelastoma. However, the patient's history, mass morphology, and histopathology pointed toward a simple degenerative cyst--previously unreported on the aortic valve. This report describes this rare finding, discusses relevant differential diagnoses, and underscores the importance of surgical intervention in such cases.
Related Concept Videos
Aortic Regurgitation I: Introduction
Aneurysm I: Introduction
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Valve Prolapse I: Introduction
Aortic Regurgitation III: Medical Management
Mitral Valve Prolapse II: Assessment and Management

