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Imaging of Von Meyenburg complexes.

L Pech1, S Favelier1, M T Falcoz1

  • 1Department of diagnostic and interventional radiology, digestive, thoracic and oncologic unit, CHU de Dijon, 14, rue Paul-Gaffarel, BP 77908, 21079 Dijon cedex, France.

Diagnostic and Interventional Imaging
|November 3, 2015
PubMed
Summary

Von Meyenburg complexes, or biliary hamartomas, are common incidental liver findings. This review details their imaging features, diagnostic challenges, and links to other ductal plate malformations and cholangiocarcinoma.

Keywords:
Bile ductsCaroli diseaseCholangiocarcinomaHamartomas

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Area of Science:

  • Hepatology
  • Radiology
  • Developmental Biology

Background:

  • Von Meyenburg complexes (VMCs), also known as biliary hamartomas, are common incidental findings in the liver.
  • They represent developmental malformations of the ductal plate, a precursor to bile ducts.

Purpose of the Study:

  • To provide an updated review on the etiopathogenesis of VMCs.
  • To illustrate the imaging characteristics of VMCs across ultrasound, CT, and MRI.
  • To discuss diagnostic pitfalls and the association of VMCs with other ductal plate malformations and cholangiocarcinoma.

Main Methods:

  • Literature review focusing on etiopathogenesis, imaging features, and clinical associations of VMCs.
  • Analysis of diagnostic challenges in differentiating VMCs from other liver lesions, particularly metastases.
  • Synthesis of recent data on the relationship between VMCs and cholangiocarcinoma.

Main Results:

  • VMCs are typically well-characterized by MRI, but can be confused with liver metastases.
  • VMCs are associated with Caroli disease and Caroli syndrome.
  • A link between VMCs and cholangiocarcinoma has been established in recent literature.

Conclusions:

  • Understanding the imaging features and potential pitfalls is crucial for accurate VMC diagnosis.
  • VMCs are part of a spectrum of ductal plate malformations.
  • Further research into the VMC-cholangiocarcinoma relationship is warranted.