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Related Concept Videos

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
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Related Experiment Video

Updated: Mar 30, 2026

Manual Therapy for a Chronic Non-Specific Low Back Pain Rat Model
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Paediatric Pain Management: Using Complementary and Alternative Medicine.

Subhadra Evans1, Jennie C I Tsao1, Lonnie K Zeltzer1

  • 1Paediatric Pain Program, Department of Paediatrics, David Geffen School of Medicine at UCLA.

Reviews in Pain
|November 4, 2015
PubMed
Summary

Managing pediatric pain is crucial for children

Area of Science:

  • Pediatric Pain Management
  • Complementary and Alternative Medicine (CAM)

Background:

  • Children experience acute and chronic pain, with infants and children potentially at higher risk for long-term pain sensitivity due to developing systems.
  • Effective management of pediatric pain is essential to alleviate suffering and prevent future pain issues.

Purpose of the Study:

  • To explore the role of complementary and alternative medicine (CAM) in managing acute and chronic pain in children from a biopsychosocial perspective.
  • To review existing research on CAM interventions for pediatric pain.

Main Methods:

  • Literature review of empirical studies on CAM interventions for pediatric pain.
  • Focus on interventions with the most research attention, including hypnotherapy, acupuncture, and music therapy.
  • Consideration of other evidence-based therapies such as yoga, massage, humor therapy, and certain biological therapies.

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Main Results:

  • Research on CAM for pediatric pain is currently limited.
  • Hypnotherapy, acupuncture, and music therapy have received the most empirical attention.
  • Evidence supports the therapeutic benefits of yoga, massage, humor therapy, and some biological therapies for pediatric pain.

Conclusions:

  • CAM should be considered as part of a comprehensive, biopsychosocial approach to managing pediatric pain.
  • Further research is needed to fully understand the efficacy and application of various CAM interventions in pediatric populations.
  • Integrating evidence-based CAM therapies can help reduce children's suffering from acute and chronic pain.