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Updated: Mar 30, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
[A case review: About a STEMI in the very elderly].
P Dupouy1, D Pongas1, V Rubimbura1
1Pôle cardiovasculaire Antony-Melun, hôpital privé d'Antony, 1, rue Velpeau, 92160 Antony, France; Clinique les Fontaines, 54, boulevard Aristide-Briand, 77000 Melun, France.
Primary angioplasty is recommended for very elderly patients (>90 years) with myocardial infarction, as age alone should not preclude reperfusion therapy. Survivors show comparable or better outcomes than their peers, justifying adherence to treatment guidelines.
Area of Science:
- Cardiology
- Geriatric Medicine
- Interventional Cardiology
Background:
- Increasing prevalence of coronary artery disease in the aging population necessitates treatment strategies for very elderly patients (>90 years).
- Limited evidence-based medicine exists for this demographic, yet registries offer guidance.
Observation:
- Age should not be a contraindication for reperfusion therapies in myocardial infarction.
- Primary angioplasty demonstrates technical success rates similar to younger populations and is the preferred treatment.
- Radial arterial access is recommended for primary angioplasty in this age group.
Findings:
- Thrombolysis has not been studied in patients >90 years, unlike in octogenarians.
- While complications like bleeding, neurological, and ischemic events are more frequent, survivors experience similar or improved survival rates.
- Initial hemodynamic compromise increases complication risks.
Implications:
- Primary angioplasty via radial access is a viable and effective treatment for very elderly myocardial infarction patients.
- Adherence to therapeutic recommendations, considering comorbidities and organ function, is crucial for optimizing outcomes in this population.
- Further research is needed to establish evidence-based guidelines for thrombolytic therapy in patients >90 years.
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