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Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
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Medication Adherence and Incident Preventable Hospitalizations for Hypertension.

Julie C Will1, Zefeng Zhang1, Matthew D Ritchey1

  • 1Division for Heart Disease and Stroke Prevention, CDC, Atlanta, Georgia.

American Journal of Preventive Medicine
|November 4, 2015
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Summary
This summary is machine-generated.

Poor adherence to hypertension (HTN) medication significantly increases the risk of potentially preventable hospitalizations (PPHs) for HTN. Addressing medication adherence can help reduce these hospitalizations and associated healthcare costs.

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Area of Science:

  • Cardiovascular Medicine
  • Health Services Research
  • Pharmacoeconomics

Background:

  • Potentially preventable hospitalizations (PPHs) for hypertension (HTN) indicate potential failures in ambulatory care.
  • HTN PPH rates have remained stagnant, suggesting a need to better understand their underlying causes.
  • While anti-HTN medication non-adherence is linked to other cardiovascular outcomes, its specific role in HTN PPHs is less understood.

Purpose of the Study:

  • To investigate the association between anti-hypertensive medication adherence and the incidence of PPHs for HTN.
  • To quantify the financial impact of PPHs for HTN related to medication adherence levels.

Main Methods:

  • A cohort analysis of individuals with HTN was conducted using the MarketScan database from 2005-2012.
  • PPH for HTN was defined using Agency for Healthcare Research and Quality criteria.
  • Adherence to anti-hypertensive medications was assessed using the Proportion of Days Covered (PDC) algorithm.

Main Results:

  • Over 9.3 million person-years of follow-up, 6,008 incident HTN PPHs were identified.
  • The rate of HTN PPHs was significantly higher for individuals with poor adherence (PDC <40%) compared to good adherence (PDC ≥80%).
  • PPH for HTN-associated costs reached $41 million over 8 years, with payments for poorly adherent patients being four times higher than for well-adherent patients.

Conclusions:

  • Poor adherence to anti-hypertensive medications is a significant risk factor for PPHs for HTN.
  • Improving medication adherence among patients with HTN is a potential strategy to decrease the burden of PPHs.
  • Targeting interventions to enhance medication adherence may reduce healthcare expenditures associated with HTN PPHs.