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Updated: Mar 30, 2026
10:28
Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
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Increased bleeding risk during percutaneous coronary interventions by arterial hypertension
Gjin Ndrepepa1, Philipp Groha1, Anna L Lahmann1
1Deutsches Herzzentrum München, Technische Universität, Munich, Germany.
Summary
Patients with arterial hypertension have a higher risk of bleeding after percutaneous coronary intervention (PCI). This study found a significant association between hypertension and increased bleeding events, including access-site and non-access-site bleeding.
Area of Science:
- Cardiology
- Interventional Cardiology
- Hypertension Research
Background:
- The relationship between arterial hypertension and bleeding complications following percutaneous coronary intervention (PCI) remains incompletely understood.
- Arterial hypertension is a prevalent comorbidity in patients with coronary artery disease.
Purpose of the Study:
- To investigate the association between arterial hypertension and the risk of bleeding in patients undergoing PCI.
- To quantify the impact of hypertension on different types of bleeding events post-PCI.
Main Methods:
- A large cohort study involving 14,180 patients who underwent PCI.
- Bleeding events were classified using the Bleeding Academic Research Consortium (BARC) criteria.
- Arterial hypertension was defined by antihypertensive medication use or specific blood pressure thresholds on multiple occasions.
Main Results:
- A significant increase in bleeding events (11.1% vs 8.9%) was observed in patients with arterial hypertension compared to those without.
- Arterial hypertension was independently associated with higher rates of any bleeding, access-site bleeding, and non-access-site bleeding.
- A history of hypertension predicted non-access-site bleeding, while systolic blood pressure during PCI predicted access-site bleeding.
Conclusions:
- Arterial hypertension is a significant risk factor for increased bleeding complications after percutaneous coronary intervention.
- These findings highlight the importance of managing hypertension in patients undergoing PCI to mitigate bleeding risks.
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