Primary Pulmonary Sequestration With Secondary Hamartomatosis Change

Area of Science:

• Radiology
• Pathology
• Medical Science

Background:

• Intralobar pulmonary sequestration (ILPS) is a congenital lung malformation.
• Typical radiologic findings include a systemic feeding artery and pulmonary venous drainage.
• Co-occurrence with hamartoma and intracranial cholesteatoma is exceptionally rare.

Observation:

• A patient presented with ILPS exhibiting unusual radiographic features.
• Computed tomography (CT) revealed a bulky mass within the pulmonary sequestration.
• Histopathology confirmed a pulmonary hamartoma with adipose and cartilage differentiation.

Findings:

• The bulky mass was diagnosed as a pulmonary hamartoma, an unusual complication of ILPS.
• The patient also presented with concurrent intracranial cholesteatoma.
• These findings represent rare manifestations of ILPS.

Implications:

• This case expands the understanding of rare ILPS presentations and complications.
• It underscores the importance of comprehensive evaluation in complex congenital lung abnormalities.
• Highlights the potential association between ILPS, hamartoma, and intracranial cholesteatoma.