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Published on: February 17, 2023
[Cerebral actinomycotic granuloma mimicking malignant brain tumor]
S V Mishinov1, A M Karchalova1, V V Stupak1
1First Department of Neurosurgery, Ya.L. Tsivian Novosibirsk Research Institute of Traumatology and Orthopedics, Novosibirsk, Russia.
Abstract:
We report a clinical case of cerebral actinomycotic granuloma that was preoperatively diagnosed as an intracerebral tumor. On the basis of a histological examination performed after lesion resection, the diagnosis of a cerebral actinomycotic granuloma was made. The article presents long-term outcomes of the surgery. The literature data on cases of various forms of cerebral actinomycosis are provided.
Insights
A rare cerebral actinomycotic granuloma was initially misdiagnosed as an intracerebral tumor. Post-surgical histological examination confirmed the actinomycosis diagnosis, with favorable long-term outcomes reported.
Area of Science:
- Neurology
- Infectious Diseases
- Pathology
Background:
- Cerebral actinomycosis is a rare fungal infection of the brain.
- It can mimic other intracranial pathologies, leading to diagnostic challenges.
Observation:
- A patient presented with symptoms suggestive of an intracerebral tumor.
- Preoperative imaging led to a diagnosis of a suspected brain tumor.
Findings:
- Histological examination after surgical resection confirmed cerebral actinomycotic granuloma.
- The patient experienced favorable long-term surgical outcomes.
Implications:
- This case highlights the importance of considering actinomycosis in the differential diagnosis of brain lesions.
- Accurate diagnosis and timely surgical intervention are crucial for managing cerebral actinomycosis.

