Related Experiment Video
Updated: Mar 30, 2026

Treating Low Back Pain in Failed Back Surgery Patients with Multicolumn-lead Spinal Cord Stimulation
Published on: June 26, 2018
Spinal Surgery and Abrupt Intrathecal Baclofen Withdrawal
1From the Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University Medical Center, Stanford, California.
Abruptly stopping intrathecal baclofen can cause severe withdrawal. Anesthesiologists must prevent baclofen interruption during surgery and manage withdrawal symptoms postoperatively.
Area of Science:
- Anesthesiology
- Neurosurgery
- Pharmacology
Background:
- Intrathecal baclofen is used for spasticity management.
- Abrupt cessation can precipitate serious withdrawal syndromes.
Observation:
- Intraoperative interruption of baclofen delivery is a risk during spinal surgery.
- Postoperative recognition and treatment of baclofen withdrawal are crucial.
Findings:
- Anesthesiologists play a key role in managing intrathecal baclofen therapy.
- Preparedness is essential to avoid intraoperative and postoperative complications.
Implications:
- Ensuring continuous baclofen delivery minimizes patient risk.
- Prompt management of withdrawal symptoms improves patient outcomes.
More Related Videos
06:51Development of an Algorithm to Perform a Comprehensive Study of Autonomic Dysreflexia in Animals with High Spinal Cord Injury Using a Telemetry Device
Published on: July 29, 2016
03:47A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
Published on: October 25, 2024
Related Concept Videos
Local Anesthetics: Clinical Application as Spinal Anesthesia
Drug Delivery: Parenteral Route
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Skeletal Muscle Relaxants: Therapeutic Uses
Classification of Skeletal Muscle Relaxants
Peripherally acting skeletal muscle relaxants interfere with the neurotransmission at the neuromuscular end plate to induce paralysis during...
Depolarizing Blockers: Pharmocokinetics