[Microcirculation in parenteral Ginkgo biloba extract therapy]

Area of Science:

• Vascular Medicine
• Pharmacology

Background:

• Arteriosclerotic lesions in extracranial brain arteries impair blood flow.
• Microcirculation is a key indicator of vascular health.

Purpose of the Study:

• To evaluate the effect of Ginkgo biloba extract on skin microcirculation in patients with arteriosclerotic lesions.
• To compare the efficacy of Ginkgo biloba extract against a placebo in enhancing peripheral blood flow.

Main Methods:

• A randomized controlled trial involving 30 patients with arteriosclerotic lesions.
• Treatment group received physiological NaCl with Ginkgo biloba extract (Tebonin).
• Control group received physiological NaCl alone.
• Skin microcirculation was measured non-invasively using a helium-neon laser on extremities.

Main Results:

• Ginkgo biloba extract administration led to a statistically significant increase in skin perfusion (p ≤ 0.01).
• The observed increase in perfusion was significantly greater compared to the control group.
• The study demonstrated a positive impact of Ginkgo biloba on peripheral blood flow.

Conclusions:

• Ginkgo biloba extract demonstrates efficacy in improving microcirculatory function.
• The findings support the use of Ginkgo biloba extract in the management of vascular diseases.
• Further research into Ginkgo biloba's role in cerebrovascular health is warranted.