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Updated: Mar 30, 2026

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
Published on: May 2, 2025
Feasibility of 4% Topical Lidocaine for Pain Management During Negative Pressure Wound Therapy Dressing Changes in
Vaidehi Agrawal1, Kirby Wilson, Roxana Reyna
1Vaidehi Agrawal, PhD, Department of Surgery, Driscoll Children's Hospital, Corpus Christi, Texas Kirby Wilson, MSN, RNC-NIC, Nursing Resources, Driscoll Children's Hospital, Corpus Christi, Texas. Roxana Reyna, BSN, RNC-NIC, WCC, CWOCN, Nursing Resources, Driscoll Children's Hospital, Corpus Christi, Texas. Mohammad Ali Emran, MD, Department of Surgery, Driscoll Children's Hospital, Corpus Christi, Texas.
Insights
Topical lidocaine effectively managed pain during negative pressure wound therapy (NPWT) dressing changes in a pediatric patient. This alternative to opioids showed no adverse effects, offering a safer pain management option.
Area of Science:
- Pain Management
- Wound Care
- Pediatric Medicine
Background:
- Opioid analgesics like morphine are standard for pediatric pain during negative pressure wound therapy (NPWT) dressing changes.
- Opioids carry significant risks, including respiratory depression and constipation, necessitating safer alternatives.
- Pediatric patients require effective and safe pain management strategies for wound care.
Observation:
- A 15-year-old male with necrotizing adenopathy was treated for NPWT.
- Four percent topical lidocaine was administered for pain control during dressing changes.
- The patient's pain levels during NPWT dressing changes were monitored.
Findings:
- Topical lidocaine significantly reduced pain associated with NPWT dressing changes.
- No adverse side effects were observed with the use of 4% topical lidocaine.
- Lidocaine provided effective analgesia in this pediatric case.
Implications:
- Topical lidocaine presents a viable, safer alternative to opioids for pediatric NPWT pain management.
- This approach may improve patient comfort and reduce opioid-related complications.
- Further research into topical lidocaine for pediatric wound care is warranted.
Background:
Opioid analgesics such as morphine are frequently used for pain management in pediatric patients undergoing dressing changes for negative pressure wound therapy (NPWT). While these medications reduce associated pain, they are also associated with adverse side effects ranging from constipation, headache, and dizziness to respiratory depression, chest wall rigidity, and death. Alternative analgesic approaches are needed for pediatric patients undergoing NPWT.
Methods:
Four percent topical lidocaine was used for pain management during dressing changes for NPWT in a 15-year-old Hispanic male with necrotizing adenopathy.
Conclusion:
The 4% topical lidocaine reduced the pain associated with dressing changes during NPWT. No adverse side effects were observed.
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