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Related Concept Videos

Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
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Bone Remodeling01:40

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Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
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Hormones and Bone Tissue01:17

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The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
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Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
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Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
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Related Experiment Video

Updated: Mar 30, 2026

Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention
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Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention

Published on: April 26, 2024

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[Osteoporosis liaison service].

Atsushi Suzuki

    Nihon Rinsho. Japanese Journal of Clinical Medicine
    |November 5, 2015
    PubMed
    Summary
    This summary is machine-generated.

    Osteoporosis poses a significant burden on aging populations, with low treatment rates increasing secondary fracture risk. Osteoporosis Liaison Service (OLS) in Japan aims to improve osteoporosis treatment and reduce fractures through comprehensive care.

    Related Experiment Videos

    Last Updated: Mar 30, 2026

    Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention
    03:56

    Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention

    Published on: April 26, 2024

    1.4K

    Area of Science:

    • Gerontology and Public Health
    • Bone Health and Osteoporosis Management

    Context:

    • Osteoporosis is a major health concern for aging societies globally.
    • Low treatment rates post-first hip fracture lead to increased secondary fracture incidence.
    • Existing Fracture Liaison Services (FLS) focus on secondary fracture prevention.

    Purpose:

    • To describe the comprehensive Osteoporosis Liaison Service (OLS) model in Japan.
    • To highlight OLS's expanded scope beyond traditional FLS, including primary fracture prevention.
    • To emphasize the role of certified OLS specialists in improving osteoporosis care.

    Summary:

    • Japanese Osteoporosis Liaison Service (OLS) integrates FLS with educational programs, bone fragility assessments, and primary fracture risk evaluations.
    • The Japan Osteoporosis Society has certified OLS specialists since 2015.
    • This integrated approach aims to enhance osteoporosis treatment efficacy.

    Impact:

    • OLS in Japan is expected to improve the management of osteoporosis.
    • The program aims to contribute to a significant reduction in clinical fractures.
    • This model offers a potential framework for broader implementation in secondary fracture prevention.