Related Experiment Video
Updated: Mar 30, 2026

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach
Published on: July 3, 2020
Measurement error models with interactions
Douglas Midthune1, Raymond J Carroll2, Laurence S Freedman3
1Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, 9609 Medical Center Drive, Room 5E122, Bethesda, MD 20892, USA midthund@mail.nih.gov.
Abstract:
An important use of measurement error models is to correct regression models for bias due to covariate measurement error. Most measurement error models assume that the observed error-prone covariate (WW ) is a linear function of the unobserved true covariate (X) plus other covariates (Z) in the regression model. In this paper, we consider models for W that include interactions between X and Z. We derive the conditional distribution of X given W and Z and use it to extend the method of regression calibration to this class of measurement error models. We apply the model to dietary data and test whether self-reported dietary intake includes an interaction between true intake and body mass index. We also perform simulations to compare the model to simpler approximate calibration models.
Related Concept Videos
Mechanistic Models: Compartment Models in Individual and Population Analysis
Random and Systematic Errors
Random and Systematic Errors
Uncertainty in Measurement: Accuracy and Precision
Systematic Error: Methodological and Sampling Errors
Sampling errors originate from improper sampling methods or the wrong sample population. These errors can be minimized by refining the sampling strategy. Defective instruments or faulty calibrations are the sources of instrumental...
Accuracy and Errors in Hypothesis Testing
In hypothesis testing, the probability of making a Type I error, denoted as α, is commonly set at 0.05. This significance level indicates a 5%...

