Related Experiment Video
Updated: Mar 30, 2026
07:24
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
13.4K
[Low grade endophthalmitis caused by P. acnes : Case report]
S Fili1, T Schilde2, K Kontopoulou2
1St.-Johannes-Hospital, Johannesstraße 9-13, 44137, Dortmund, Deutschland. sofiafili86@hotmail.com.
Summary
Low grade endophthalmitis, often mistaken for uveitis, can be successfully treated with combined operative therapy. This approach, including pars plana vitrectomy and intravitreal antibiotics, offers a solution for this challenging post-cataract surgery complication.
Area of Science:
- Ophthalmology
- Infectious Diseases
Background:
- Low grade endophthalmitis is a chronic inflammation often misdiagnosed as noninfectious uveitis.
- Corticosteroid treatment is frequently ineffective for this indolent form of endophthalmitis.
Observation:
- A case of low grade endophthalmitis caused by Propionibacterium acnes following cataract surgery is presented.
- Diagnostic challenges in identifying this specific type of endophthalmitis are highlighted.
Findings:
- Successful treatment was achieved through a combined operative approach.
- The therapy included pars plana vitrectomy, intravitreal antibiotics, and posterior capsulectomy.
Implications:
- This case underscores the importance of considering infectious causes in chronic post-surgical inflammation.
- Combined operative therapy offers a viable and effective treatment strategy for Propionibacterium acnes-induced endophthalmitis.
Keywords:
Autoimmune uveitisCataractLow grade endophthalmitisPosterior capsulectomyPropionibacterium acnesMore Related Videos
Related Concept Videos
01:22Microbiome of the Eye
37
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
37
01:25Endocarditis I: Introduction
760
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
760
01:27Acne Infection
48
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
48
01:25Glaucoma: Overview
1.7K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K
01:28Angle Closure Glaucoma: Treatment
1.6K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.6K