Related Experiment Video

Updated: Mar 30, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

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[Low grade endophthalmitis caused by P. acnes : Case report]

S Fili1, T Schilde2, K Kontopoulou2

  • 1St.-Johannes-Hospital, Johannesstraße 9-13, 44137, Dortmund, Deutschland. sofiafili86@hotmail.com.

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|November 5, 2015
PubMed

Insights

Low grade endophthalmitis, often mistaken for uveitis, can be successfully treated with combined operative therapy. This approach, including pars plana vitrectomy and intravitreal antibiotics, offers a solution for this challenging post-cataract surgery complication.

Area of Science:

  • Ophthalmology
  • Infectious Diseases

Background:

  • Low grade endophthalmitis is a chronic inflammation often misdiagnosed as noninfectious uveitis.
  • Corticosteroid treatment is frequently ineffective for this indolent form of endophthalmitis.

Observation:

  • A case of low grade endophthalmitis caused by Propionibacterium acnes following cataract surgery is presented.
  • Diagnostic challenges in identifying this specific type of endophthalmitis are highlighted.

Findings:

  • Successful treatment was achieved through a combined operative approach.
  • The therapy included pars plana vitrectomy, intravitreal antibiotics, and posterior capsulectomy.

Implications:

  • This case underscores the importance of considering infectious causes in chronic post-surgical inflammation.
  • Combined operative therapy offers a viable and effective treatment strategy for Propionibacterium acnes-induced endophthalmitis.
Keywords:
Autoimmune uveitisCataractLow grade endophthalmitisPosterior capsulectomyPropionibacterium acnes

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