Related Experiment Video
Updated: Mar 30, 2026

Author Spotlight: Advancing Syphilis Research — Innovations in Treponema pallidum Cultivation and Genetic Engineering
Published on: January 24, 2025
Objectives:
The aim of this study was to evaluate the epidemiological situation of syphilis in the Slovak Republic in the period of the past two decades.
Background:
In last decade, the incidence of syphilis has decreased in European countries by 13%. However, several countries reported an increase in the trend of syphilis.
Methods:
Cases of syphilis reported to the National Health Information Center in the Slovak Republic were statistically evaluated.
Results:
In the first decade syphilis possessed an increase rate 262.5% and 127.6% in five subsequent year intervals, and then the rate fluctuated and showed minimal decrease in the last three years. The highest rate 7.3 per 100,000 population documented in 2009. The peak in the Bratislava region reached 36.36 in 2000. Epidemic was documented in marginalized group in East region. Early syphilis was the most frequent stage observed in both decades but late and no specified cases increased in the last period. The M/F rate was up to 1.7, the most frequently recorded age category was 15-24 years.
Conclusion:
These results indicate a requirement for developing a comprehensive control and educational program in the overall population, particularly in marginalized groups, and improving case management by health providers (Fig. 3, Ref. 20).
Related Concept Videos
Sexually Transmitted Infections
Infectious Diseases and Their Occurrence
Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Bacterial Phylum Spirochaetes
Increasing Function

