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Torulopsis glabrata infections in Singapore: a 4-year study
The Journal of Hygiene
|April 1, 1977
Abstract:
During the period 1971-4, Torulopsis glabrata formed 42% of yeasts isolated from 5677 clinical specimens from patients with cancers, diabetes mellitus, chronic renal failure, pregnacy or major surgical operations complicated by mycotic infections. The significance of T. glabrata in these patients is discussed.
Insights
Torulopsis glabrata was a common yeast in patients with serious health conditions between 1971-4. This opportunistic fungus was found in 42% of yeast isolates from at-risk individuals, highlighting its clinical significance.
Area of Science:
- Medical Mycology
- Clinical Microbiology
Background:
- Torulopsis glabrata is an opportunistic fungal pathogen.
- Patients with compromised immune systems are susceptible to mycotic infections.
Purpose of the Study:
- To determine the prevalence of Torulopsis glabrata in clinical specimens.
- To assess the clinical significance of T. glabrata in high-risk patient groups.
Main Methods:
- Retrospective analysis of clinical yeast isolates.
- Identification of yeast species from 5677 specimens collected between 1971-4.
Main Results:
- Torulopsis glabrata accounted for 42% of all yeast isolates.
- High isolation rates were observed in patients with cancers, diabetes mellitus, chronic renal failure, pregnancy, and post-surgical complications.
Conclusions:
- Torulopsis glabrata is a significant cause of mycotic infections in immunocompromised and high-risk patients.
- The prevalence of T. glabrata underscores the need for vigilance in diagnosing and managing fungal infections in these populations.