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Published on: September 22, 2019
Vogt-Koyanagi-Harada syndrome and Crohn's disease: an exceptional association
Ahlem Souguir1, Aya Hammami2, Wafa Dahmeni2
1Department of Gastroenterology, University Hospital Sahloul, Sousse, Tunisia souguirahlem@yahoo.fr.
Abstract:
Vogt-Koyanagi-Harada disease (VKH) is a rare, multisystem disease of melanocyte-containing organs. It is characterized by diffuse, granulomatous inflammation involving various organs. It has been reported to occur in association with other autoimmune disorders. We report the case of a female patient who was diagnosed with VKH at the age of 4 years and who was treated with corticosteroids until the age of 16. Twenty years later, Crohn's disease was diagnosed, with a severe flare-up. Three cases of VKH associated with ulcerative colitis have previously been reported anecdotally but, to our knowledge, this is the first case occurring in association to Crohn's disease.
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