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Updated: Mar 30, 2026

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
Published on: March 22, 2012
Post endodontic Aspergillosis in an immunocompetent individual
Aadithya B Urs1, Hanspal Singh2, Kalpana Nunia3
1MDS, Professor & Head, Department of Oral & Maxillofacial Pathology,Maulana Azad Institute of Dental Sciences, New Delhi, India, BSZ Marg, New Delhi-110002.
Non-invasive aspergillosis can occur in the maxillary sinus after endodontic treatment. Early diagnosis and treatment with antifungals like itraconazole lead to complete recovery.
Area of Science:
- Mycology
- Endodontics
- Oral and Maxillofacial Surgery
Background:
- Non-invasive aspergillosis can affect immunocompetent individuals.
- Post-endodontic complications may include fungal sinusitis.
- Maxillary antrum involvement is a known manifestation.
Observation:
- A 35-year-old female presented with painful nasomaxillary swelling.
- A retained root fragment after endodontic treatment failure and extraction led to the swelling.
- Histopathology confirmed Aspergillus fungal hyphae.
Findings:
- Systemic itraconazole treatment resulted in symptom improvement within 3 months.
- Complete resolution of non-invasive aspergillosis was achieved in 6 months.
- Aspergilloma infection should be considered in differential diagnosis for post-endodontic swelling.
Implications:
- Highlights the importance of thoroughness in endodontic procedures.
- Emphasizes considering fungal infections in persistent post-operative swelling.
- Suggests a treatment protocol for non-invasive aspergillosis in this context.
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