Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

6.6K
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
6.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bio-Inspired lipid nanovesicles (iNVs) incorporating membrane proteins from healthy tendon stem cells for targeted protein restoration in tendinopathic <i>in vitro</i> model.

Artificial cells, nanomedicine, and biotechnology·2026
Same author

Transcultural adaptation and validation of the 4-Domain Sports PROM into Italian.

Journal of ISAKOS : joint disorders & orthopaedic sports medicine·2024
Same author

Disease activity assessment for juvenile idiopathic arthritis in transitional care.

Reumatismo·2024
Same author

Exploring current understanding and philosophies of orthopaedic surgery in the sports person.

Journal of orthopaedics·2023
Same author

Ossification of the posterior capitellum: description of a new pathology and its radiological appearance.

Archives of orthopaedic and trauma surgery·2022
Same author

Isolated radial tears of the lateral meniscus midbody: a case series of professional athletes treated with outside-in repair.

Musculoskeletal surgery·2022

Related Experiment Video

Updated: Mar 30, 2026

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
04:19

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device

Published on: November 8, 2024

1.6K

Teriparatide in Fracture Non-Unions.

C Coppola1, A Del Buono2, N Maffulli3

  • 1Department of Orthopaedic and Trauma Surgery, Hospital "S. Maria di Loreto Nuovo", Naples, Italy.

Translational Medicine @ Unisa
|November 5, 2015
PubMed
Summary

Teriparatide may improve healing in nonunions of lower limb fractures. This case series showed adequate bone callus and sound union in four patients treated with teriparatide (parathyroid hormone).

Keywords:
Fracturesinternal fixationnon-unionsurgeryteriparatide

More Related Videos

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner
04:41

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner

Published on: June 6, 2025

1.5K
Protocol for Developing a Femur Osteotomy Model in Wistar Albino Rats
05:43

Protocol for Developing a Femur Osteotomy Model in Wistar Albino Rats

Published on: August 31, 2022

3.5K

Related Experiment Videos

Last Updated: Mar 30, 2026

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
04:19

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device

Published on: November 8, 2024

1.6K
Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner
04:41

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner

Published on: June 6, 2025

1.5K
Protocol for Developing a Femur Osteotomy Model in Wistar Albino Rats
05:43

Protocol for Developing a Femur Osteotomy Model in Wistar Albino Rats

Published on: August 31, 2022

3.5K

Area of Science:

  • Orthopedic Surgery
  • Pharmacology
  • Regenerative Medicine

Background:

  • Limited data exists on teriparatide for fracture healing.
  • Nonunions after traumatic lower limb fractures pose significant management challenges.

Purpose of the Study:

  • To evaluate the potential of teriparatide in enhancing the healing of traumatic lower limb fracture nonunions.
  • To assess clinical and radiographic outcomes following teriparatide administration.

Main Methods:

  • A therapeutic case series (Level IV evidence) involving four patients.
  • Patients with nonunions post-open fixation of lower limb fractures received teriparatide.
  • Outcomes were assessed through clinical evaluation and radiography.

Main Results:

  • Teriparatide administration led to adequate bone callus formation at the nonunion site in all patients.
  • All patients demonstrated clinical and radiographic evidence of sound fracture union.
  • The treatment appeared to facilitate bone regeneration and healing.

Conclusions:

  • Teriparatide shows promise in managing delayed unions and nonunions.
  • Potential mechanisms include inducing an angiogenetic response that combats nonunion development.
  • Further research is warranted to clarify teriparatide's efficacy in fracture healing.