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Updated: Mar 30, 2026

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
FDG-PET/CT for Detection of Extramedullary Disease in 2 Pediatric Patients With AML
Motohiro Matsui1, Junko Yamanaka, Hiroyuki Shichino
1Departments of *Pediatrics †Radiology, Division of Nuclear Medicine, National Center for Global Health and Medicine, Tokyo, Japan.
Abstract:
Positron emission tomography combined with computed tomography (PET/CT) is a promising diagnostic procedure for the detection of extramedullary disease (EMD) in acute myeloid leukemia. We studied 2 children with acute myeloid leukemia who underwent PET to assess for EMD at diagnosis as well as in remission. We detected 5 EMD lesions in 2 cases with PET, only 2 of which were detectable on clinical examination. Our cases show PET's increased sensitivity over physical examination alone in assessing and monitoring the extent of this disease.
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