Related Experiment Video
Updated: Mar 30, 2026
Introduction of Intracapsular Rotary-cut Procedures IRCP: A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
Published on: January 17, 2019
Management of fibroids in perimenopausal women
Stefano R Giannubilo1, Andrea Ciavattini, Felice Petraglia
1aDepartment of Clinical Science, Polytechnic University of Marche, Ancona bDepartment of Molecular and Developmental Medicine, Obstetrics, and Gynecology, University of Siena, Siena cDepartment of Experimental and Clinical Medicine, Faculty of Medicine dDepartment of Information Engineering, Polytechnic University of Marche, Ancona, Italy *Mario Castellucci and Pasquapina Ciarmela contributed equally to the writing of this article.
Purpose Of Review:
This article reviews fibroids management in the perimenopausal period, and addresses future directions in care.
Recent Findings:
Aromatase inhibitors, selective estrogen receptor modulators and antiprogestogens for medical management and minimally surgical techniques are promising treatments.
Summary:
The disease and the symptoms may persist in the peri and postmenopausal periods. The assumption that they will resolve with the onset of the menopause is too simplistic and not always valid. The number of perimenopausal women who wish to retain their uterus for reasons other than childbearing is increasing. The accurate diagnosis of these conditions may result in minor surgical or medical treatments being directed at the specific pathology and may avoid the need for major surgery.
More Related Videos
11:29Surgical Techniques to Optimize Ovarian Reserve during Laparoscopic Cystectomy for Ovarian Endometrioma
Published on: January 22, 2022
05:32Author Spotlight: Investigating the Relationship Between FSH and Pathophysiological Changes in Perimenopausal Women - Insights from a Mouse Model
Published on: August 11, 2023
Related Concept Videos
01:28Menopause
01:30Hormonal Control of the Ovarian Cycle
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
01:22Hormonal Regulation of the Menstrual Cycle
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
01:30Irritable Bowel Syndrome III: Medical and Nursing Management
01:28Infertility in Females
Endometriosis, a condition characterized by abnormal growth of...