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Related Experiment Video

Updated: Mar 30, 2026

Stereotactic Radiosurgery for Gynecologic Cancer
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Radiosurgery for Pediatric Brain Tumors.

Erin S Murphy1,2, Samuel T Chao1,2, Lilyana Angelov2

  • 1Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio.

Pediatric Blood & Cancer
|November 5, 2015
PubMed
Summary

Radiosurgery shows promise for treating pediatric brain tumors, especially residual or recurrent cases. Further research is needed to establish clear guidelines and minimize potential toxicities in children.

Keywords:
craniopharyngiomaependymomagliomamedulloblastomapediatricradiosurgery

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Area of Science:

  • Pediatric neuro-oncology
  • Radiation oncology
  • Neurosurgery

Background:

  • The role of radiosurgery in treating pediatric brain tumors remains unclear.
  • Radiosurgery may be beneficial for unresectable, residual, or recurrent pediatric brain tumors previously treated with radiotherapy.

Purpose of the Study:

  • To evaluate the utility and safety of radiosurgery for pediatric brain tumors.
  • To identify potential indications and treatment guidelines for pediatric radiosurgery.

Main Methods:

  • Review of available evidence on radiosurgery for pediatric brain tumors.
  • Analysis of local control rates and toxicities associated with pediatric radiosurgery.

Main Results:

  • Evidence suggests radiosurgery can achieve good local control for some primary pediatric brain tumors.
  • Radiosurgery is a viable option for limited residual disease or focal recurrences in pediatric brain tumors.
  • Potential toxicities associated with pediatric radiosurgery are significant and require careful consideration.

Conclusions:

  • Radiosurgery demonstrates utility in specific pediatric brain tumor scenarios, including residual or recurrent disease.
  • Prospective studies are essential to establish evidence-based guidelines for pediatric radiosurgery indications and treatment.
  • Minimizing unique toxicities is a critical goal for future pediatric radiosurgery research and application.