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Updated: Mar 30, 2026

Innovative Strategies for Organ Preservation in Heart Transplantation: Uniform Cooling Preservation and Ex-situ Normothermic Perfusion
Published on: November 28, 2025
Heart Procurement from a Donor on Venovenous ECMO Support
Gopal Singh1, Masaki Tsukashita, Mauer Biscotti
1From the *Section of Thoracic Surgery, Columbia University Medical Center, New York, New York; and †Division of Cardiothoracic Surgery, Columbia University Medical Center, New York, New York.
Abstract:
We report the case of a 37-year-old woman with acute respiratory distress syndrome and became a candidate for organ donation after anoxic brain injury and was on a venovenous extracorporeal membrane oxygenation (VV-ECMO) support. On preoperative evaluation and gross examination, the donor's heart was acceptable for heart transplantation to a 62-year-old female patient with a history of nonischemic cardiomyopathy with a HeartMate II mechanical assist device. Orthotopic heart transplantation was successfully performed in the recipient. We report a case that suggests that the procurement of a heart from a donor on ECMO support can potentially expand the donor heart pool in carefully selected patients.
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