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Adolescent suicide and testosterone.

Timothy R Rice1, Leo Sher1

  • 1.

International Journal of Adolescent Medicine and Health
|November 5, 2015
PubMed
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Male suicide rates increase during adolescence, potentially linked to testosterone. This review explores how high testosterone levels in adolescent males may impair emotion regulation, contributing to suicide risk.

Area of Science:

  • Neuroendocrinology
  • Adolescent Psychology
  • Suicidology

Background:

  • Completed suicide is significantly more prevalent in men than women.
  • Suicide incidence escalates sharply during adolescence.
  • Testosterone, the primary male sex hormone, is hypothesized to mediate this increased suicide frequency in men.

Purpose of the Study:

  • To review existing literature on the association between testosterone and completed suicide in men.
  • To elucidate potential biological mechanisms linking testosterone to suicide risk.
  • To propose that elevated adolescent testosterone levels may impair emotion regulation, contributing to suicide.

Main Methods:

  • Literature review of studies examining testosterone levels and suicide.
  • Description of the neural systems involved in emotion regulation.
Keywords:
aggressionanhedoniaemotion regulationimpulsivitymen’s mental healthsuicidetestosterone

Related Experiment Videos

  • Analysis of testosterone's specific effects on these neural systems.

    • Main Results:

    • Testosterone's influence on adolescent neurodevelopment and emotion regulation is a key area of investigation.
    • Potential mechanisms include testosterone's impact on brain regions critical for emotional processing and impulse control.
    • The literature suggests a plausible biological pathway connecting high testosterone levels to altered emotional responses.

    Conclusions:

    • High levels of testosterone during adolescence may negatively impact the emotion regulation system.
    • This neurobiological effect could partially explain the higher rates of completed suicide observed in adolescent males.
    • Further research is warranted to explore clinical implications and develop targeted interventions.