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Facile and Efficient Preparation of Tri-component Fluorescent Glycopolymers via RAFT-controlled Polymerization
Published on: June 19, 2015
Glycopolymer-Grafted Polymer Particles for Lectin Recognition
Michinari Kohri1, Tatsuo Taniguchi2, Keiki Kishikawa2
1Division of Applied Chemistry and Biotechnology, Graduate School of Engineering, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba, 263-8522, Japan. kohri@faculty.chiba-u.jp.
Abstract:
Glycopolymers bearing carbohydrates have an advantage in protein recognition that is attributable to the multivalent effect (cluster effect) of side-chain carbohydrates. A variety of surface-modified polymer particles have been prepared concurrently with the development of new synthetic technology. Here we describe a synthetic method of glycopolymer-grafted polymer particles by surface-initiated living radical polymerization, i.e., atom-transfer radical polymerization (ATRP) and photoiniferter polymerization, for specific lectin recognition.

