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Related Experiment Videos

Prostatic epithelial polyp of the prostatic urethra.

S Satoh1, T Ujiie, T Kubo

  • 1Department of Urology, Iwate Medical University School of Medicine, Morioka, Japan.

European Urology
|January 1, 1989
PubMed
Summary

Prostatic epithelial polyps, characterized by specific antigen markers, were identified in ten male patients. These polyps presented with common urinary symptoms and were confirmed via transurethral resection.

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Area of Science:

  • Urology
  • Pathology
  • Gastroenterology

Background:

  • Prostatic epithelial polyps are rare benign growths in the male urinary tract.
  • Understanding their histological and immunohistochemical features is crucial for diagnosis.

Purpose of the Study:

  • To report ten cases of prostatic epithelial polyps.
  • To describe their clinical presentation, histological characteristics, and immunohistochemical profile.

Main Methods:

  • Retrospective analysis of ten patient cases.
  • Specimens obtained via transurethral resection.
  • Histopathological examination and indirect immunoperoxidase staining for prostate-specific antigen and prostatic acid phosphatase.

Main Results:

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  • Ten male patients aged 27-69 (mean 44) presented with gross hematuria, microhematuria, hematospermia, and dysuria.
  • All polyps exhibited a papillary or polypoid configuration with glandular structures resembling prostate tissue.
  • Prostate-specific antigen and prostatic acid phosphatase were detected in the epithelial cells of the polyps.

Conclusions:

  • Prostatic epithelial polyps appear to represent hyperplasia of prostate-specific antigen and prostatic acid phosphatase-positive epithelial cells.
  • These findings suggest a potential origin from prostatic glands or ducts.