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Oral transmucosal administration of dexmedetomidine for sedation in 4 dogs
Anne E Cohen1, Sara L Bennett1
1Animal Hospital Emergency Department (Cohen), Animal Hospital Behavior Department (Bennett), VCA Berwyn Animal Hospital, 2845 S. Harlem Ave, Berwyn, Illinois 60402, USA.
Abstract:
Injectable dexmedetomidine (DM) is widely used for sedation, restraint, anxiolysis, and analgesia in veterinary medicine. Oral transmucosal dexmedetomidine (OTM DM) has been evaluated in horses, cats, and humans, but not in dogs. In this case series, OTM DM (mean dose of 32.6 μg/kg body weight) was given in the buccal pouch to 4 aggressive dogs in a hospital setting. Two of the dogs were subsequently euthanized, and in the other 2, sedation was reversed with atipamezole. Satisfactory sedation was achieved in all cases.
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