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Vitelline cyst in the rat ileum
Takafumi Oshikata1, Azusa Kobayashi1, Shino Kumabe1
1LSI Medience Corporation, 1285 Kurisaki-machi, Uto, Kumamoto 869-0425, Japan.
Journal of Toxicologic Pathology
|November 6, 2015
Summary
A rare congenital vitelline duct anomaly, a vitelline cyst, was found in a laboratory rat. This is the first reported case of such a cyst in a rat
Area of Science:
- Veterinary Pathology
- Developmental Biology
- Gastrointestinal Research
Background:
- Congenital anomalies of the vitelline duct are uncommon in animal models.
- Meckel's diverticulum is the only previously reported congenital vitelline duct anomaly in rats.
Observation:
- An 8 mm cyst was identified on the antimesenteric surface of the ileal serosa in a 10-week-old female rat.
- Histological examination revealed the cyst resembled the ileum but lacked communication with the lumen.
Findings:
- The observed cyst was diagnosed as a vitelline cyst, originating from the vitelline duct.
- This represents a novel finding, as no spontaneous vitelline cysts have been previously documented in rats.
Implications:
- This case expands the known spectrum of congenital vitelline duct anomalies in rats.
- Provides a potential new model for studying vitelline duct-related conditions in research animals.
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