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Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
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Newer therapies for multiple sclerosis

Alasdair Coles1

  • 1Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.

Annals of Indian Academy of Neurology
|November 6, 2015
PubMed

The newer immunotherapies for multiple sclerosis (fingolimod, natalizumab, dimethyl fumarate, teriflunomide, alemtuzumab) offer advantages of efficacy or tolerability over the injectable therapies of the 1990s. But they also have greater risks. As further treatments emerge (daclizumab and ocrelizumab are likely to be licensed in the next two years), the physician needs to be able to place them within a complex landscape of drugs and a specific treatment strategy, which may be an "escalation" or "induction" approach. Whilst on treatment, neurologist and patient need to be vigilant to signs of disease breakthrough or adverse effects.

Keywords:
Multiple sclerosisNewer drugsdisease burdenefficacysafety

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