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Role of proteomics in physiologic and pathologic conditions of dentistry: Overview
Thukanayakanpalayam Ragunathan Yoithapprabhunath1, Ramadas Madhavan Nirmal2, Arumugam Santhadevy3
1Department of Oral and Maxillofacial Pathology, Vivekanandha Dental College for Women, Tiruchengode, Tamilnadu, India.
Abstract:
Proteomics is the study of structure and function of proteins in a large scale. For any living organism, preteins are considered to be the vital part because of its role in metabolic pathways of cells. These proteins not only play a role in physiological condition of the cell but also in altered manner during pathologic conditions. These altered proteins in diseased conditions are called as biomarkers. Several such biomarkers were identified in oral diseaes. This review is a brief note on proteins involved in odontogenesis and list of altered proteins proteins identified in various dental and oral diseases. The knowledge about the role of proteomics in dentistry and the importance of proteomic studies in early diagnosis and prognostic part of oral diseases helps in appliction of precised and sucessful treatment.
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