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Updated: Mar 30, 2026
Quantification of Hypopigmentation Activity In Vitro
Published on: March 6, 2019
A clinical study on oral lichen planus with special emphasis on hyperpigmentation
Ravi Teja Chitturi1, Pandian Sindhuja2, R Arjun Parameswar3
1Department of Oral Pathology, SIBAR Institute of Dental Sciences, Guntur, Andhra Pradesh, India.
Background:
Oral lichen planus (OLP) is a unique disorder affecting generally the older age group. Numerous studies have been done on various aspects of OLP such as pathogenesis, rate of malignant transformation, etc. However, very few studies are available with respect to clinical features especially association of hyperpigmentation and OLP. This study aims at studying the clinical aspects of OLP and study the association between hyperpigmentation and OLP in a south Indian population.
Materials And Methods:
A total of 58 patients with OLP who attended the outpatient department of our institution were included in the study and a complete history, followed by thorough intraoral examination was done. All the data were recorded and assessed for statistical analysis using SPSS software.
Results:
We found that the male to female ratio affected with OLP was 1:1 and the most common form of OLP that was seen was the reticular subtype. Also, buccal mucosa was the most common affected site and more than 60% patients had hyperpigmentation associated with the site affected by OLP. We found a statistically significant relation between the reticular type of OLP and the older age group (51-70 years) with hyperpigmentation.
Conclusion:
Although further studies are required to say anything conclusively, post-inflammatory changes occurring the mucosa due to OLP could be a cause for hyperpigmentation in the sites affected.
