Recent advancements in fluoride: A systematic review.

Area of Science:

• Dentistry
• Preventive Medicine
• Public Health

Background:

• Fluoride has been a cornerstone of dental caries prevention for over 30 years.
• Extensive research has established fluoride's efficacy in reducing tooth decay.
• Current scientific efforts aim to optimize fluoride delivery and efficacy.

Purpose of the Study:

• To review recent advancements in fluoride research for dental caries prevention.
• To synthesize current knowledge on improving fluoride's effectiveness in clinical practice.
• To provide an overview of novel strategies in fluoride therapy.

Main Methods:

• A comprehensive literature search was conducted across 21 electronic databases and the World Wide Web.
• Relevant journals were hand-searched, and authors were contacted for additional information.
• Study validity was systematically assessed using predefined checklists and independent reviewer screening.

Main Results:

• Fluoride remains a critical agent in preventive dentistry.
• Research is actively exploring new strategies to enhance fluoride's caries-preventive capabilities.
• Various fluoride delivery systems, including varnishes, gels, mouth rinses, and toothpastes, are widely used.

Conclusions:

• Fluoride therapy continues to be a highly effective intervention for preventing dental caries.
• Ongoing research promises further improvements in fluoride's role in oral health.
• The development of enhanced fluoride strategies is crucial for future dental public health initiatives.